研究简介
长期从事干细胞和呼吸系统再生研究。目前获国家海外高层次人才（青年项目），国自然面上基金等支持。目前以通讯作者、第一作者或共同第一作者身份在Nature, Cell Research, Developmental Cell, Cell Reports等权威杂志上发表学术论文多篇。
荣誉奖励
1. 广州市优秀专家
2. 国家重大人才项目入选者（青年）
代表性成果
1. Zhang P.*, Zhai X.*, Huang B.*, Sun S., Wang W., Zhang M. 2023, Highly efficient generation of blastocyst-like structures from spliceosomes-repressed mouse totipotent blastomere-like cells, Sci China Life Sci.1674-7305.
2. Vojtek, M., Zhang, J., Sun, J., Zhang, M. #, & Chambers, I#. 2022, Differential repression of Otx2 underlies the capacity of NANOG and ESRRB to induce germline entry, Stem cell reports, 17(1): 35-42. (#, co-corresponding author)
3. Yu S*, Zhou C*, He J*, Yao Z, Huang X, Rong B, Zhu H, Wang S, Chen S, Wang X, Cai B, Zhao G, Chen Y, Xiao L, Liu H, Qin Y, Guo J, Wu H, Zhang Z, Zhang M, Zhao X, Lan F, Wang Y, Chen J, Cao S, Pei D, Liu J. BMP4 drives primed to naïve transition through PGC-like state, 2022, Nat Communications, 19;13(1):2756 (*, co-first author)
4. Liu, J., Gao, M., He, J., Wu, K., Lin, S., Jin, L., Chen, Y., Liu, H., Shi, J., Wang, X., Chang, L.，Lin, Y.，Zhao, Y. L.，Zhang, X.，Zhang, M.，Luo, G. Z.，Wu, G.，Pei, D.，Wang, J.，Bao, X.，Chen, J. 2021, The RNA m(6)A reader YTHDC1 silences, retrotransposons and guards ES cell identity Nature, 591, 322-326.
5. Zhang, JC*., Zhang, M* #., Acampora D., Vojtek M., Yuan DT., Simeone, A., Chambers I#, 2018, Otx2 restricts entry to the mouse germline, Nature. 562 (7728), 595-599, 2018 (*, co-first author, #, co-corresponding author).
6. Zhang, M., Leitch, H.G., Tang, W.W.C., Festuccia, N., Hall-Ponsele, E., Nichols, J., Surani, M.A., Smith, A., and Chambers, I. , 2018, Esrrb Complementation Rescues Development of Nanog -Null Germ Cells, Cell Reports, 22, 332-339.
7. Barakat, T.S., Halbritter, F., Zhang, M., Rendeiro, A.F., Perenthaler, E., Bock, C., and Chambers, I., 2018, Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells, Cell Stem Cell, 23, 276-288 e278.
8. Gou, L.T., Kang, J.Y., Dai, P., Wang, X., Li, F., Zhao, S., Zhang, M., Hua, M.M., Lu, Y., Zhu, Y., et al., 2017, Ubiquitination-Deficient Mutations in Human Piwi Cause Male Infertility by Impairing Histone-to-Protamine Exchange during Spermiogenesis, Cell, 169, 1090-1104 e1013.
9. Wu, Y*., Zhou, H*., Fan, X*., Zhang, Y*., Zhang, M*., Wang, Y., Xie, Z., Bai, M., Yin, Q., Liang, D., Tang, W., Liao, J., Zhou, C., Liu, W., Zhu, P., Guo, H., Pan, H., Wu, C., Shi, H., Wu, LG., Tang, FC., Li, JS., 2015, Correction of a genetic disease by CRISPR Cas9-mediated gene editing in mouse spermatogonial stem cells, Cell Research, 25, 67-79. (*, co-first author)
10. Zhang, M., Zhou, H., Zheng, C., Xiao, J., Zuo, E., Liu, W., Xie, D., Shi, Y., Wu, C., Wang, H., Li, DS., Li, JS., 2014, The roles of testicular c-kit positive cells in de novo morphogenesis of testis, Scientific Reports, 4, 5936.
