研究简介
主要从事药物新剂型及其重大品种产业化的研究，积极参与国家药用吸入气雾剂氟利昂替代的相关政策制订，是2000版、2010版､2015版、2020版中国药典吸入制剂相关通则与测定法的主要起草人，全程参与我国经口吸入制剂从无到有的发展历程和标准建立过程。先后负责国家863、国家重点攻关的多个项目；主译国外专著《固体口服制剂的研发:药学理论与实践》、《呼吸道药物递送的基本理论与实践》；发表70余篇SCI/核心论文；获40余项中国专利授权／欧洲专利授权；近五年负责研发的吸入制剂有10个产品、14个品规获批上市，完成国内首个吸入溶液剂、吸入粉雾剂的一致性评价；获批国内首个吸入抗生素；负责生物创新药新冠重组蛋白疫苗V-01、重组新型冠状病毒融合蛋白二价苗的临床研究，均被国家纳入紧急使用。
荣誉奖励
1. 第十四届全国人大代表
2. 中国药学会制药工程专业委员会主任委员
3. 第九、十、十一、十二届国家药典委员会委员
4. 国务院政府特殊津贴
5. “新世纪百千万人才工程”国家级人选
6. 上海市“三八红旗手”
7. 全国优秀科技工作者
代表性成果
1. Yan Chen, Lei Zhou, Ling Yuan, Zhenhai Zhang, Xuan Liu, Qingqing Wu, Fang Jin（*）,10.2147/IJN.S32476, Formulation, Optimization, Characterization, and Pharmacokinetics of Progesterone Intravenous Lipid Emulsion for Traumatic Brain Injury Therapy. Pharmaceutical Science, 43/171.
2. Xiaoxia Ye, Juan Ma, Yongjian Yang, Fang Jin（*), 10.1039/c3ay42047g, Analysis of 21 phthalate leachables in metered dose inhalers by gas chromatography tandem mass spectrometry. SCI, Chemistry, 44/110.
3. Jiahua Deng, Weihui Cai, Fang Jin（*）, 10.1016/j.ijpharm. 2014.04.003 A novel oil-in-water emulsion as a potential adjuvant for influenza vaccine. Development, characterization, stability and in vivo evaluation. SCI, Pharmaceutical Science, 68/219
4. LL Shen, YN Liu, HJ Shen, C Wen, YL Jia, XW Dong, F Jin（*）, XP Chen, Y Sun, QM Xie ,10.1016/j.intimp. 2013.12.021, Inhalation of glycopyrronium inhibits cigarette smoke-induced acute lung inflammation in a murine model of COPD SCI, Pharmacology, 50/301.
5. Feihu Wang a b, Yun Wang a, Xiao Zhang a, Wenjun Zhang a, Shengrong Guo a, Fang Jin b（*), 10.1016/j.jconrel.2013.11.020, Recent progress of cell-penetrating peptides as new carriers for intracellular cargo delivery SCI, Pharmacology, toxicology and Pharmaceutics, 3/183.
6. Jieqiong You, Ying Wang, Haifeng Chen, Fang Jin（*), 10.3389/fphar.2023.1192970, RIPK2: a promising target for cancer treatment, SCI, 生物化学与分子生物学 81/297.
7. Xuan-Yi Wang, Syed Faisal Mahmoodd, Fang Jine (#), Wee Kooi Cheahg, Muhammad Ahmadh, Mian Amjad Sohaili, Waheed Ahmadj, Vijaya K. Suppank, Muneeba Ahsan Sayeedl, Shobha Luxmim, Aik-Howe Teon, Li Yuan Leeo, Yang-Yang Qi, Rong-Juan Pei, Wei Deng, Zhong-Hui Xu, Jia-Ming Yang, Yan Zhang, Wu-Xiang Guan and Xiong Yu, 10.1080/22221751.2022.2088406 , Efficacy of heterologous boosting against SARS-CoV-2 using a recombinant interferon-armed fusion protein vaccine (V-01): a randomized, double-blind and placebo-controlled phase III trial. SCI, Infection Diseases 8/96.
8. 一种吸入用布地奈德混悬液的制备方法，中国，ZL202111002317.5
9. 一种氟替卡松原料药粒径的测试方法，中国，ZL202010240869.9
10. 真空履带式烘箱生产依维莫司固体分散体的方法，中国，ZL202210231728.X
