董骥研究员
教育经历
2008.09-2012.07，海南大学，海洋生物学，学士
2012.09-2015.07，华东师范大学，生物化学与分子生物学，硕士
2015.09-2020.07，北京大学，细胞生物学，博士
工作经历
2020.07-2021.05，生物岛实验室，研究员
2021.05至今，广州实验室，研究员
研究简介
董骥课题组致力于利用单细胞组学、生物信息学、类器官培养、基因编辑等多种技术研究发育生物学和再生医学等相关课题。发表SCI论文超过30篇，引用超过3200次，其中以通讯或第一作者身份在国际权威杂志上发表学术论文共计17篇，包括Cell，Cell Stem Cell，Cell Research，National Science Review，Aging Cell等。
人才头衔与荣誉奖励
1.国家优秀青年科学基金
人才头衔与荣誉奖励
1.国家优秀青年科学基金
代表性成果
# (co-) corresponding author; * (co-) first author.
1. Complexin-1 enhances ultrasound neurotransmission in the mammalian auditory pathway. Liu ML, Wang CL, Huo LF, Cao J, Mao XG, He ZQ, Hu CX, Sun HJ, Deng WJ, He WY, Chen YF, Gu MF, Liao JY, Guo N, He XY, Wu Q, Chen JK, Zhang LB, Wang XQ, Shang CP, Dong J#. Nature Genetics (2024) 1-13
2. Spatiotemporal transcriptome atlas reveals the regional specification of the developing human brain. Li Y, Li Z, Wang C, Yang M, He Z, Wang F, Zhang Y, Li R, Gong Y, Wang B, Fan B, Wang C, Chen L, Li H, Shi P, Wang N, Wei Z, Wang Y, Jin L, Du P, Dong J#, Jiao J. Cell (2023) 186(26): 5892-5909. e22.
3. Cross-species comparison illuminates the importance of iron homeostasis for splenic anti-immunosenescence. He Z, He W, Hu C, Liao J, Deng W, Sun H, Huang Q, Chen W, Zhang L, Liu M, Dong J#. Aging Cell (2023) e13982
4. Brain circuits for retching-like behavior. Huo L, Ye Z, Liu M, He Z, Huang M, Li D, Wu Q, Wang Q, Wang X, Cao P, Dong J#, Shang C. National Science Review (2023) nwad256
5. Characterization of mesenchymal stem cells in human fetal bone marrow by single-cell transcriptomic and functional analysis. Zhang P, Dong J*, Fan X, Yong J, Yang M, Liu Y, Zhang X, Lv L, Wen L, Qiao J, Tang F, Zhou Y.Signal Transduction and Targeted Therapy (2023) 8 (1), p.126
6. Spatially-resolved expression landscape and gene-regulatory network of human gastric corpus epithelium. Dong J*, Wu X, Zhou X, Gao Y, Wang C, Wang W, He W, Li J, Deng W, Liao J, Wu X, Lu Y, Chen A, Wen L, Fu W, Tang F. Protein & Cell (2022) pwac059, https://doi.org/10.1093/procel/pwac059
7. Integrating single-cell datasets with ambiguous batch information by incorporating molecular network features. Dong J*, Zhou P, Wu Y, Chen Y, Xie H, Gao Y, Lu J, Yang J, Zhang X, Wen L, Li T, Tang F. Briefings in Bioinformatics (2021) bbab366
8. Single-cell RNA-seq analysis unveils a prevalent epithelial/mesenchymal hybrid state during mouse organogenesis. Dong J*, Hu Y, Fan X, Wu X, Mao Y, Hu B, Guo H, Wen L, Tang F.
Genome Biology (2018) 19 (1), 31
9. Spatial transcriptomic survey of human embryonic cerebral cortex by single-cell RNA-seq analysis. Fan X, Dong J*, Zhong S, Wei Y, Wu Q, Yan L, Yong J, Sun L, Wang X, Zhao Y, Wang W, Yan J, Wang X, Qiao J, Tang F. Cell Research (2018) 28 (7), 730-745
10. Single-cell RNA-Seq analysis maps development of human germline cells and gonadal niche interactions. Li L, Dong J*, Yan L, Yong J, Liu X, Hu Y, Fan X, Wu X, Guo H, Wang X, Zhu X, Li R, Yan J, Wei Y, Zhao Y, Wang W, Ren Y, Yuan P, Yan Z, Hu B, Guo F, Wen L, Tang F, Qiao J. Cell Stem Cell (2017) 20 (6), 858-873. e4
2. Spatiotemporal transcriptome atlas reveals the regional specification of the developing human brain. Li Y, Li Z, Wang C, Yang M, He Z, Wang F, Zhang Y, Li R, Gong Y, Wang B, Fan B, Wang C, Chen L, Li H, Shi P, Wang N, Wei Z, Wang Y, Jin L, Du P, Dong J#, Jiao J. Cell (2023) 186(26): 5892-5909. e22.
3. Cross-species comparison illuminates the importance of iron homeostasis for splenic anti-immunosenescence. He Z, He W, Hu C, Liao J, Deng W, Sun H, Huang Q, Chen W, Zhang L, Liu M, Dong J#. Aging Cell (2023) e13982
4. Brain circuits for retching-like behavior. Huo L, Ye Z, Liu M, He Z, Huang M, Li D, Wu Q, Wang Q, Wang X, Cao P, Dong J#, Shang C. National Science Review (2023) nwad256
5. Characterization of mesenchymal stem cells in human fetal bone marrow by single-cell transcriptomic and functional analysis. Zhang P, Dong J*, Fan X, Yong J, Yang M, Liu Y, Zhang X, Lv L, Wen L, Qiao J, Tang F, Zhou Y.Signal Transduction and Targeted Therapy (2023) 8 (1), p.126
6. Spatially-resolved expression landscape and gene-regulatory network of human gastric corpus epithelium. Dong J*, Wu X, Zhou X, Gao Y, Wang C, Wang W, He W, Li J, Deng W, Liao J, Wu X, Lu Y, Chen A, Wen L, Fu W, Tang F. Protein & Cell (2022) pwac059, https://doi.org/10.1093/procel/pwac059
7. Integrating single-cell datasets with ambiguous batch information by incorporating molecular network features. Dong J*, Zhou P, Wu Y, Chen Y, Xie H, Gao Y, Lu J, Yang J, Zhang X, Wen L, Li T, Tang F. Briefings in Bioinformatics (2021) bbab366
8. Single-cell RNA-seq analysis unveils a prevalent epithelial/mesenchymal hybrid state during mouse organogenesis. Dong J*, Hu Y, Fan X, Wu X, Mao Y, Hu B, Guo H, Wen L, Tang F.
Genome Biology (2018) 19 (1), 31
9. Spatial transcriptomic survey of human embryonic cerebral cortex by single-cell RNA-seq analysis. Fan X, Dong J*, Zhong S, Wei Y, Wu Q, Yan L, Yong J, Sun L, Wang X, Zhao Y, Wang W, Yan J, Wang X, Qiao J, Tang F. Cell Research (2018) 28 (7), 730-745
10. Single-cell RNA-Seq analysis maps development of human germline cells and gonadal niche interactions. Li L, Dong J*, Yan L, Yong J, Liu X, Hu Y, Fan X, Wu X, Guo H, Wang X, Zhu X, Li R, Yan J, Wei Y, Zhao Y, Wang W, Ren Y, Yuan P, Yan Z, Hu B, Guo F, Wen L, Tang F, Qiao J. Cell Stem Cell (2017) 20 (6), 858-873. e4